CHOQ APEX Glutathione

the master antioxidant + so much more

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Click below to explore the science behind APEX Glutathione:


Clinically-Researched Ingredients


100% Vegan


Glutathione is the most important antioxidant in your body.

A master immunomodulator, it’s now recognized as one of the top immune-boosting nutrients of all time.  It’s also critical for healthy detoxification and inflammation response, but its beneficial effects extend to nearly every system in the body.

CHOQAPEX Glutathione is a research-based, highly absorbable form of glutathione, but it’s also a synergistic formula of 12 ingredients that work together to elevate the body’s natural production and utilization of this vital compound.

Ready to take your detox, immunity, and focus to the next level?  Try CHOQ APEX Glutathione today!



Technology has improved our lives in countless ways, but it’s also made the world far more toxic than it used to be. 

Since the 1940s, tens of millions of unique chemical compounds have been synthesized or isolated by humans, and most of them have had minimal safety testing performed on them.

Pesticides, heavy metals, flame retardants, artificial fragrances and colorings, preservatives, solvents…the list is endless.  

Gone are the days when simply eating right and exercising was enough to maintain optimal health. If we want to retain our vitality in the midst of all this toxicity, we need all the help we can get. 

Glutathione is a molecule that your body naturally produces that binds to all kinds of different toxins and helps to safely shuttle them out of your body, where they belong.

It’s also deeply connected to immune health, as it supports the balance between two very important branches of the immune system: the Th1 and Th2 responses.  

Its benefits are extremely wide-ranging, however.  

Glutathione supports every system in the body because every cell requires it to function optimally.  It supports mood, focus, inflammation response, joint health, heart health, liver function, and even post-workout recovery. 

There are plenty of glutathione supplements out there, but unfortunately, many of them contain a kind of glutathione called ‘reduced glutathione’ which is not the most bioavailable form of this crucial antioxidant.  

CHOQ APEX Glutathione uses a clinically-researched form of glutathione called ‘S-Acetyl-Glutathione’ that has been demonstrated to absorb 70% better than standard glutathione.

In addition to providing you with a highly stable, highly bioavailable form of glutathione, it also includes adaptogenic herbs and nutrients that were selected because they enhance your body’s natural production and utilization of glutathione while promoting healthy energy, mood, and focus.  

Scroll down to learn more about what makes APEX uniquely powerful. 


CHOQ is a plant-forward company, which is why we always enhance our formulas with powerful herbs and mushrooms that bring out the best in each nutrient, providing you with additional benefits to help you lead a life of radiant vitality.

Apex Glutathione contains high potency standardized extracts of Reishi, Bacopa, and Jiaogulan, adaptogens that enhance glutathione production while promoting healthy mood, energy, focus, and immunity.


Expertly formulated to optimize multiple pathways that regulate glutathione

Solid formulation logic based on biochemistry = results you can feel.

Your body uses multiple different enzymes to synthesize, recycle, and transport glutathione to where it needs to be.

Some of these enzymes include:

  • Glutathione S-transferase (GST) binds glutathione to toxins for elimination
  • Glutathione Peroxidase (GPx) – transfers glutathione to free radicals, allowing antioxidant function
  • Glutathione Reductase (GR) – recycles glutathione after it has been used up by neutralizing too many free radicals, allowing each glutathione molecule to be active for longer

APEX Glutathione’s ingredients were blended based on how they interact with these enzymes and many other aspects of glutathione metabolism.

This is science-based formulation at its finest. 


















































All formulated to synergistically support the body’s glutathione production while providing additional benefits for mood, focus, and cellular energy production.




























Welcome to the most advanced glutathione available.
























the nitty gritty

Click on the dropdown menus to explore the science behind each ingredient.

Emothion® Ultra High Absorption S-Acetyl-Glutathione

Patent Pending PCT/EP2014/073957

Emothion® S-Acetyl-Glutathione has been scientifically demonstrated to absorb 70% better than “reduced” L-glutathione.

The addition of the acetyl group to the glutathione molecule significantly increases its stability and allows it to be absorbed in the intestines without being broken down.

This ingredient supports:

  • Healthy detoxification by attaching to toxic compounds and removing them from the body
  • Liver health by assisting the liver with the removal of chemicals and other toxins
  • Immune health by promoting the balance between the Th1 and Th2 family of immune signaling molecules and supporting healthy white blood cell function
  • Healthy inflammation response within the brain, heart, muscles, and joints
  • Healthy mood, memory, and focus
  • Post-workout recovery
  • Mitochondrial function (cellular energy production)
  • Healthy aging through antioxidant protection
Bacognize® Standardized Bacopa Monnieri Extract

Bacognize® is a clinically-researched standardized extract of the Ayurvedic herb Bacopa monnieri.

Although many may be familiar with bacopa’s positive effects on mood and focus, few are aware that it also works with the body’s glutathione system.

The subject of 7 studies, Bacognize® has been clinically proven to enhance memory and focus.  It is sustainably grown in India and standardized via HPLC to contain serotonin-active bacopa glycosides and other bioactive phytochemicals.

This ingredient supports:

  • Multi-antioxidant activation through promotion of NRF2
  • Enhanced activity of the Glutathione S-Transferase (GST) enzyme, helping glutathione bind to toxins
  • Enhanced activity of the Glutathione Peroxidase (GPx) enzyme, assisting glutathione with the neutralization of free radicals
  • Optimal memory and cognitive performance by promoting healthy levels of acetylcholine
  • Healthy mood by promoting serotonin signaling (via SABGs: Serotonin-Active Bacopa Glycosides)
  • Optimal stress response and calm focus by promoting healthy GABA levels
  • Healthy neurological inflammation response
JiaogulanEx™ Standardized Jiaogulan Extract

Also known as Gynostemma pentaphyllum, Jiaogulan is a powerful adaptogenic plant used by herbalists in Asia for thousands of years to promote energy, mood, focus, and overall vitality.

Many of the active phytochemicals that make this plant so potent are called saponins, and are structurally related to the compounds in ginseng.  While ginseng has 28 different saponins, however, Jiaogulan contains over 80 distinct saponin phytochemicals.

The most potent Jiaogulan extract available, JiaogulanEx is standardized to 98% gypenosides (the specific name for the saponins in Jiaogulan).

This ingredient supports:

  • Enhanced activity of the Glutathione Peroxidase (GPx) enzyme, assisting glutathione with the neutralization of free radicals
  • Enhanced activity of the Glutathione Reductase (GR) enzyme, assisting the body with regenerating oxidized glutathione back into its active form
  • Generation of the endogenous antioxidant Superoxide Dismutase (SOD)
  • Immune health through supporting healthy cytokine balance and antibody production
  • Healthy inflammation response
  • Optimal energy levels by promoting mitochondrial energy production
  • Healthy mood and cognitive function
Ultra High Potency 16x Organic Reishi Extract

Reishi, also known as Ganoderma lucidum, is among the most famous of all adaptogenic mushrooms.  It has been revered for millennia for its effects on mood, immunity, and overall wellbeing.

Because this is a 16:1 extract (the most potent available), a 150-milligram serving is the equivalent of 2.4 grams of dried reishi mushrooms.

Unlike other reishi products that use cheap mycelium that’s mostly grain and contains no actual mushroom material, this organic, ultra high-potency extract is made entirely from fruiting bodies, in accordance with the way that reishi has been used for thousands of years.

This ingredient supports:

  • Enhanced activity of the Glutathione S-Transferase (GST) enzyme, helping glutathione bind to toxins
  • Enhanced activity of the Glutathione Peroxidase (GPx) enzyme, assisting glutathione with the neutralization of free radicals
  • Immune function by promoting healthy T-cell balance (CD4+/CD8+ ratio)
  • Healthy inflammation response via activation of multiple antixodidant pathways
  • Healthy mood and focus
NAC (N-Acetyl-Cysteine)

The glutathione molecule is comprised of three amino acids: L-glutamine, L-glycine, and L-cysteine.  Among these, L-cysteine is by far the most important (rate-limiting) ingredient when it comes to glutathione synthesis.

NAC, a more bioavailable form of cysteine than L-cysteine, also supports immune health in ways that go beyond its ability to help the body produce glutathione.  

This ingredient supports:

  • Enhanced glutathione production by providing the rate-limiting amino acid precursor, cysteine 
  • Healthy mood, liver function, and detoxification
  • Immune health by supporting optimal T-cell activation
R-Alpha-Lipoic Acid

Also known as thiotic acid, lipoic acid is a powerful antioxidant compound that your body naturally makes in order to assist with mitochondrial function, maintain healthy glucose levels, and help glutathione do its job.

There are two versions of this compound often found in supplements: the less potent version is simply called ‘Alpha-Lipoic Acid’, while a version known as ‘R-Alpha-Lipoic Acid’ is approximately twice the strength because it only contains the R isomer as opposed to a 50/50 ratio of the active R form and the relatively inactive S form.

Using this form was the obvious choice because we strive to always use the highest potency, most bioactive version of every nutrient possible.

This ingredient supports:

  • Enhanced activity of three of the major glutathione system enzymes, including Glutathione Peroxidase (GPx), Glutathione Reductase (GR), and Glutathione S-Transferase (GST), promoting global glutathione optimization
  • Cellular energy production
  • Generation of the endogenous antioxidant Superoxide Dismutase (SOD)
  • Healthy insulin function and blood sugar levels
  • Circulatory health via promotion of nitric oxide synthesis
Quatrefolic® 5-MTHF (Bioactive Folate)

Patent Pending PCT/IB2015/060027

Also known as Vitamin B9, Folate is an extremely important molecule for a number of reasons.  It governs DNA replication and expression, neurotransmitter synthesis, red blood cell production, mitochondrial function, and also takes part in glutathione synthesis.

Unfortunately, many products are still using cheap, synthetic folic acid, a totally human-made chemical that works very poorly in a significant portion of the populace due to various common gene mutations such as MTHFR.

Quatrefolic® is a clinically-researched, fully bioavailable, and natural folate, a far cry from synthetic folic acid in terms of stability and efficacy. 

Known sometimes as L-methylfolate or 5-MTHF, this compound is bioidentical in the sense that it is the same molecular structure as the folate that is in your body right now, enabling it to go to work immediately.

This ingredient supports:

  • Enhanced glutathione production by converting homocysteine to cysteine, a critical amino acid that serves as part of the “backbone” of the glutathione molecule
  • Positive mood by supporting healthy synthesis of dopamine, serotonin, and epinephrine
  • Healthy red blood cell generation
  • Healthy DNA replication
  • Cellular energy production via reduced mitochondrial gene mutation
  • Immune function via healthy T-cell production
  • Cardiovascular function via enhanced homocysteine metabolism
Bioactive Vitamin B12 as Methylcobalamin

Vitamin B12 is another B vitamin that works closely with folate in order to generate cysteine, a crucial amino acid that forms the “backbone” of the glutathione molecule.

As with folate, much of the B12 used in supplements is an inferior, synthetic variety called cyanocobalamin that contains cyanide and is not found anywhere in nature.

The bioactive form of B12 that is necessary for cysteine generation is known as methylcobalamin.  This is the exact molecular form that is already in your body, and thus it can–like natural folate–go to work immediately to promote healthy energy levels, detoxification, focus, and mood.

This ingredient supports:

  • Enhanced glutathione production by converting homocysteine to cysteine, a critical amino acid that serves as part of the “backbone” of the glutathione molecule
  • Positive mood by supporting healthy synthesis of dopamine, serotonin, and epinephrine
  • Healthy energy levels via mitochondrial energy production
  • Healthy red blood cell generation
  • Cardiovascular function via enhanced homocysteine metabolism
Bioactive Vitamin B6 as Pyridoxal 5'-Phospate (PLP)

Vitamin B6 is necessary for the generation of cysteine, a critical amino acid precursor to glutathione.  It’s also an essential cofactor that helps your body manufacture neurotransmitters like dopamine, serotonin, and GABA, making it an ideal mood and cognitive support nutrient.

Many supplements contain a cheaper form of B6 called pyridoxine hydrochloride, a molecular form that’s not necessarily problematic, but is less active than PLP as the body must first convert it to PLP before it can be used.

As always, we chose the most bioactive form of B6 to ensure that you get results.

This ingredient supports:

  • Enhanced glutathione production by assisting in the generation of cysteine
  • Healthy mood by supporting the synthesis of serotonin and dopamine
  • Calm focus by supporting the synthesis of GABA
  • Cardiovascular wellness through enhanced homocysteine metabolism
Bioactive Vitamin B2 as Riboflavin 5'-Phosphate (R5P)

Also known as Vitamin B2, Riboflavin is a crucial activator of glutathione as well as other B vitamins, such as folate, B6, and niacin.  It also supports neurological health by enhancing mitochondrial energy production.

As with the other B vitamins in APEX Glutathione, we selected R5P over standard riboflavin because it’s the most active form, a fully plug-and-play version of riboflavin that does not require additional modification in order to go to work enhancing gluatathione production within your cells.

This ingredient supports:

  • Enhanced activity of the Glutathione Reductase (GR) enzyme, assisting the body with regenerating oxidized glutathione
  • Healthy folate metabolism through activation of the MTHFR enzyme
  • Healthy energy levels via mitochondrial energy production (via FAD, an essential part of the electron transport chain)
  • Neurological health by supporting ATP synthesis in the brain 
Selenium Glycinate

In order for your body’s glutathione system to work optimally, there are several minerals that must be in ample supply.  One of the most essential of these minerals is selenium.  In addition to supporting healthy detoxification, selenium also promotes healthy immunity and thyroid function.

There are several molecular forms of selenium available, and some are much bioavailable than others.  

We chose selenium glycinate because, unlike inorganic forms like sodium selenite, it’s bound to an amino acid and thus is in a form that’s much easier for the body to work with.

This ingredient supports:

  • Enhanced activity of the Glutathione Peroxidase (GPx) enzyme, assisting glutathione with the neutralization of free radicals
  • Immune health via promotion of B-cell and T-cell function
  • Healthy inflammation response via regulation of eicosanoids
  • Thyroid health by supporting healthy conversion of T4 to T3
Molybdenum Glycinate

Molybdenum (pronouced “muh-lib-duh-nuhm”) is a little-known trace mineral that assists the body with detoxification through several different pathways.

Molybdenum is necessary for the body to process sulfur-containing compounds such as glutathione and cysteine, ensuring that they’re being properly used by the body.

As with selenium, there are many forms of molybdenum available, some of which are easier to absorb than others.  We chose this more natural form because it’s bound to an amino acid and thus is highly recognizable by the body.

This ingredient supports:

  • Enhanced metabolism of glutathione and cysteine (via sulfite oxidase)
  • Healthy detoxification via the upregulation of enzymes that neutralizes many common toxins (aldehyde oxidase and xanthine oxidase)
  • Vitality and longevity by increasing antioxidant generation



The active ingredient in CHOQ Apex Glutathione is 70% more bioavailable than standard reduced glutathione

Click the button below to see the scientific references

Every cell in your body needs glutathione. That’s why it supports wellness across the board.

APEX Glutathione is a dynamic, multipurpose supplement that promotes:

APEX Glutathione Supports:

Healthy Detoxification and Liver Function

Glutathione is the single most important compound your body makes when it comes to healthy detoxification and liver function.  When your levels are optimized, your body has an easier time getting rid of anything that’s not supposed to be there.  Try APEX and your liver will thank you.

Immune System Intelligence

Glutathione is profoundly helpful for the immune system.  When levels are optimal, this supports a healthy balance between Th1 and Th2 cytokines and cells.  In plain English, this means that your immune system works smarter, not harder.   Ingredients like Selenium, Reishi, and Jiaogulan also support healthy immune function and histamine balance.

Mood, Focus, and Serotonin Production

Reishi, Bacopa, Folate, Vitamin B12, and Jiaogulan greatly enhance glutathione’s brain-supportive properties.  The Bacopa extract in APEX has been standardized to contain significant quantities of Serotonin Active Bacopa Glycosides (SABGs), making it a great choice to support both healthy mood and focus.  

Antioxidant Protection and Healthy Aging

Glutathione is the body’s master antioxidant, so it’s crucial to protect your cells against free radical damage, whether those free radicals come from inside or outside of your body.  As we age, our production of glutathione tends to decrease, so supplementing is a great way to support graceful aging.


Healthy Inflammation Response

Because glutathione supports immune intelligence, it also supports a healthy inflammation response throughout your entire body.  Whether you’re looking for support with your joints, muscles, bones, brain, blood vessels, digestive tract, or anywhere else, APEX Glutathione can help you function at full capacity.

Are you ready to try the most advanced glutathione on the market?

On its own, glutathione is already an extremely powerful tool to support your vitality and help you deal with the toxicity of the world.

But APEX Glutathione’s professionally-formulated combination of 12 ingredients creates a synergy that puts it in a category of its own.  

It’s also the reason that you can actually feel it working and so won’t have to worry about whether or not you wasted your money.  

Try APEX and you’ll never want to be without it.   

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