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Action 2.0: the research

ACTION 2.0: the research 

Scroll down to view the references for the studies on the proprietary ingredients in Action 2.0 and learn more about what makes it such an extraordinary product.

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Capros® Organic Amla Extract

one of ayurveda’s most celebrated superfruit adaptogens

Capros® is the premier research-based blood flow booster: a multi-patented certified organic Amla extract that’s backed by 11 studies to support:

  • Over 50% increased production of Nitric Oxide and Glutathione
  • Healthy muscle recovery and inflammation response
  • Healthy blood glucose and cholesterol levels
  • Heart muscle strength
  • Athletic endurance
  • Liver detoxification

REFERENCES

Biswas, T. K., Chakrabarti, S., Pandit, S., Jana, U., & Dey, S. K. (2014). Journal of Herbal Medicine, 4(4), 188-194. doi:10.1016/j.hermed.2014.09.002

Fatima, N., Pingali, U., & Muralidhar, N. (2014). Phytomedicine, 21(5), 579-585. doi:10.1016/j.phymed.2013.10.024

Fatima, N., Usharani, P., & Muralidhar. (2013) doi:10.2147/dmso.s46341

Islam, I., Biswajit, A., Mazumder, U., Gupta, M., Ghosal, S. (2008) Pharmacologonline 2, 255-264

Khanna, S., Das, A., Spieldenner, J., Rink, C., & Roy, S. (2015). Journal of Medicinal Food, 18(4), 415-420. doi:10.1089/jmf.2014.0178

Pingali, U., Fatima, N., & Pilli, R. (2014). Pharmacognosy Research, 6(1), 29. doi:10.4103/0974-8490.122914

Thirunavukkarasu, M., Selvaraju, V., Tapias, L., Sanchez, J. A., Palesty, J. A., & Maulik, N. (2015). Journal of Physiology and Biochemistry, 71(4), 623-633. doi:10.1007/s13105-015-0426-8

Usharani et al.,  (2014). International Journal of Pharmaceutical Sciences and Research 5(7): 2687-2697.

Usharani, P., Merugu, P. L., & Nutalapati, C. (2019). BMC Complementary and Alternative Medicine, 19(1). doi:10.1186/s12906-019-2509-5

Usharani, P., SudhaRani, E., KiranKishore, K., & Raveendranath, P. (2017). International Journal Of Pharmaceutical Sciences And Research, 8(10), 4138-4146. doi:10.13040/ijpsr.0975-8232.8(10).4138-46

ElevATP® Ancient Peat and Apple Extract

Clinically-studied support for your trillions of mitochondria

When it comes to sustained, stimulant-free energy, it’s all about ATP.  ElevATP® is an adaptogenic blend made of ancient peat and apple extract that has been clinically proven to enhance mitochondrial ATP production.

ElevATP® supports:

  • Increased lean muscle and strength
  • Enhanced power output and training volume
  • Healthy collagen formation
  • Mitochondrial biogenesis (via PGC-1a)
  • Healthy expression of inflammatory mediators such as NFkB, COX-2, and TNFa
  • Synthesis of glutathione, the body’s master antioxidant and chemical detox compound

REFERENCES

Reyes, Tania & Nemzer, B. & Argumedo, Ruby & Shu, C. & Huynh, L. & Pietrzkowski, Z.. (2013). Effect of the dietary supplement ElevATP on blood ATP level: An acute pilot clinical study. journal of aging research and clinical practice. 2. 178-184.

Reyes, Tania & Shu, C. & Argumedo, Ruby & Nemzer, B. & Pietrzkowski, Z. (2014). The effect of ElevATP™on whole blood ATP levels: a single dose, cross over clinical study.. journal of aging reserch and clinical practice. 1. 1-5.

Joy, Jordan & Vogel, Roxanne & Moon, Jordan & Falcone, Paul & Mosman, Matt & Pietrzkowski, Zbigniew & Reyes, Tania & Kim, Michael. (2016). Ancient peat and apple extracts supplementation may improve strength and power adaptations in resistance trained men. BMC Complementary and Alternative Medicine. 16. 10.1186/s12906-016-1222-x.

ENOVITA® and leucoselect® advanced Grape seed extracts

A unique blend that combines long- and short-chain opc’s from the two most clinically-studied grape seed extracts.

Leucoselect® and ENOVITA® are the two most researched grape seed extracts on the market and together provide unmatched blood flow, collagen, and cardiovascular support.

This powerhouse OPC blend supports:

  • Collagen stabilization through inhibition of enzymes that break down joint tissues
  • Enhanced capillary strength and peripheral circulation
  • Post-workout recovery and healthy inflammation response
  • Neutralization of mitochondria-generated free radicals
  • Healthy blood pressure already in the normal range
  • Enhanced blood flow at the level of microcirculation

REFERENCES

Aldini, G., Carini, M., Piccoli, A., Rossoni, G., & Facino, R. M. (2003).  Life sciences, 73(22), 2883–2898. https://doi.org/10.1016/s0024-3205(03)00697-0

Belcaro, Gianni & Ledda, Andrea & Hu, Shu & Cesarone, Maria & Feragalli, Beatrice & Dugall, Mark. (2013).  eCAM. 2013. 313142. 10.1155/2013/313142.

Carini, M., Stefani, R., Aldini, G., Ozioli, M., & Facino, R. M. (2001). Planta medica, 67(8), 714–717. https://doi.org/10.1055/s-2001-18353

Carini, M., Maffei Facino, R., Aldini, G., Callonii, M. T., Bombardelli, E., & Morazzoni, P. (1998).  International journal of cosmetic science, 20(4), 203–215. https://doi.org/10.1046/j.1467-2494.1998.176606.x

Carini, M., Aldini, G., Bombardelli, E., Morazzoni, P., & Maffei Facino, R. (2000).  Life sciences, 67(15), 1799–1814. https://doi.org/10.1016/s0024-3205(00)00771-2

Colzani, M., Criscuolo, A., De Maddis, D., Garzon, D., Yeum, K. J., Vistoli, G., Carini, M., & Aldini, G. (2014).  Journal of pharmaceutical and biomedical analysis, 91, 108–118. https://doi.org/10.1016/j.jpba.2013.12.024

Cristoni, A. et al. (1998). Acta Phytoterapeutica, 1(2), 52-56

Dell’Agli, M., et al. (2015).  7th International Conference on Polyphenols and Health. Oct. 27-30, 2015

Facino, R. M., Carini, M., Aldini, G., Berti, F., Rossoni, G., Bombardelli, E., & Morazzoni, P. (1999).  Life sciences, 64(8), 627–642. https://doi.org/10.1016/s0024-3205(98)00605-5

Gabetta, B., Fuzzati, N., Griffini, A., Lolla, E., Pace, R., Ruffilli, T., & Peterlongo, F. (2000).  Fitoterapia, 71(2), 162–175. https://doi.org/10.1016/s0367-326x(99)00161-6

Jin, G., Asou, Y., Ishiyama, K., Okawa, A., Kanno, T., & Niwano, Y. (2018). Journal of food science, 83(4), 1149–1152. https://doi.org/10.1111/1750-3841.14098

Jin, G. & Aikebaier, Aobulikasimu & Piao, J. & Aibibula, Z. & Koga, D. & Ochi, H. & Ishiyama, K. & Kanno, T. & Niwano, Yoshimi & Okawa, Atsushi & Asou, Yoshinori. (2018).  Journal of Medical and Dental Sciences. 65. 45-50. 10.11480/jmds.650201.

Ikai, H., Nakamura, K., Kanno, T., Shirato, M., Meirelles, L., Sasaki, K., & Niwano, Y. (2013).  Biocontrol science, 18(3), 137–141. https://doi.org/10.4265/bio.18.137

Maffei Facino, R., Carini, M., Aldini, G., Bombardelli, E., Morazzoni, P., & Morelli, R. (1994).  Arzneimittel-Forschung, 44(5), 592–601.

Maffei Facinó, R., Carini, M., Aldini, G., Berti, F., Rossoni, G., Bombardelli, E., & Morazzoni, P. (1996).  Planta medica, 62(6), 495–502. https://doi.org/10.1055/s-2006-957956

Maffei Facino, R., Carini, M., Aldini, G., Calloni, M. T., Bombardelli, E., & Morazzoni, P. (1998).  Planta medica, 64(4), 343–347. https://doi.org/10.1055/s-2006-957448

Nakamura, K., Shirato, M., Ikai, H., Kanno, T., Sasaki, K., Kohno, M., & Niwano, Y. (2013).  PloS one, 8(3), e60053. https://doi.org/10.1371/journal.pone.0060053

Natella, F., Belelli, F., Gentili, V., Ursini, F., & Scaccini, C. (2002).  Journal of agricultural and food chemistry, 50(26), 7720–7725. https://doi.org/10.1021/jf020346o

Nishioka, Hiroshi & Fujii, Hajime & Sun, Buxiang & Aruoma, Okezie. (2006). Toxicology. 226. 181-7. 10.1016/j.tox.2006.06.017.

Pietta, P., Simonetti, P., & Mauri, P. (1998). Journal of Agricultural and Food Chemistry, 46(11), 4487-4490. doi:10.1021/jf980310p

Pinna, C., Morazzoni, P., & Sala, A. (2017).  Phytomedicine : international journal of phytotherapy and phytopharmacology, 25, 39–44. doi:10.1016/j.phymed.2016.12.015

Seo, K., Jung, S., Park, M., Song, Y., & Choung, S. (2001).  Biological & pharmaceutical bulletin, 24(5), 592–593. https://doi.org/10.1248/bpb.24.592

Simonetti, P., Ciappellano, S., Gardana, C., Bramati, L., & Pietta, P. (2002). Journal of agricultural and food chemistry, 50(21), 6217–6221. https://doi.org/10.1021/jf011412+

Sri Harsha, P.S.C. & Gardana, Claudio & Simonetti, Paolo & Spigno, Giorgia & Lavelli, Vera. (2013).  Bioresource Technology. 140C. 263-268. 10.1016/j.biortech.2013.04.092.

Ursini, Fulvio & Tubaro, Franco & Rong, James & Sevanian, Alex. (1999). Nutrition Reviews. 57. 241 – 249. 10.1111/j.1753-4887.1999.tb06951.x.

RHODIOLIFE® AUTHENTIC SIBERIAN RHODIOLA EXTRACT

SUSTAINABLY WILDCRAFTED IN THE ALTAI MOUNTAINS.  LAB-VERIFIED FOR POTENCY.

Rhodiola is arguably the most famous herb on the planet for enhancing athletic performance, mood, and focus.  Unfortunately, the market is full of adulterated Rhodiola extracts that haven’t been properly vetted.

That’s why we use a third-party verified Rhodiola rosea, wildcrafted in the Altai mountains of Siberia and standardized to contain consistent quantities of 6 different key phytochemicals using UHPLC (Ultra High Performance Liquid Chromatography).

Rhodiolife® supports:

  • Mitochondrial energy production
  • Healthy cognitive function
  • Neurotransmitter optimization and positive mood
  • Healthy circulation and oxygen transport
  • Game-changing endurance and stamina

REFERENCES

Abidov, M., Crendal, F., Grachev, S., Seifulla, R., & Ziegenfuss, T. (2003). Bulletin of Experimental Biology and Medicine, 136(6), 585-587. doi:10.1023/b:bebm.0000020211.24779.15

Abidov, M., Grachev, S., Seifulla, R. D., & Ziegenfuss, T. N. (2004). Bulletin of Experimental Biology and Medicine, 138(1), 63-64. doi:10.1023/b:bebm.0000046940.45382.53

Bystritsky, A., Kerwin, L., & Feusner, J. D. (2008). The Journal of Alternative and Complementary Medicine, 14(2), 175-180. doi:10.1089/acm.2007.7117

Dimpfel, W., Schombert, L., Vega-Morales, T., & Wiebe, J. C. (2016). Pharmacology & Pharmacy, 07(07), 290-303. doi:10.4236/pp.2016.77036

S7™ NITRIC-OXIDE BOOSTING SUPERFOOD BLEND

230% INCREASE IN NITRIC OXIDE PRODUCTION.  NATURALLY.

S7™ is a blend of 7 superfoods that is clinically demonstrated to increase your nitric oxide production by 230% at a dose of only 50mg per day.

S7 supports:

  • Enhanced blood flow
  • Free radical scavenging
  • Cellular oxygen delivery
  • Cognitive health (via nitric oxide production)
  • Athletic performance

REFERENCES

Nemzer, B. V., Centner, C., Zdzieblik, D., Fink, B., Hunter, J. M., & König, D. (2018). Oxidative stress or redox signalling – new insights into the effects of a proprietary multifunctional botanical dietary supplement. Free radical research, 52(3), 362–372. https://doi.org/10.1080/10715762.2017.1390228