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ASHWAGANDHA: the research 



Scroll down to view the references for the specific studies done on this Ashwagandha extract and learn more about what makes it such an extraordinary product.

The ultimate in stress, mood, and hormone support.

Shoden® is the most potent Ashwagandha extract available.  Standardized to 35% withanolides, it’s 14 times the potency of many common Ashwagandha products (which often only contain 2.5%).

Human clinical research has demonstrated Shoden’s ability to support:

  • Healthy mood and focus
  • Hormone health
  • Emotional well-being
  • Restorative sleep
  • Healthy stress hormone synthesis


Lopresti, Adrian L. PhDa,b,?; Smith, Stephen J. MAa,b; Malvi, Hakeemudin MBBS, MDc; Kodgule, Rahul, MBBSd. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine 98(37):pe17186, September 2019.
Lopresti AL, Drummond PD, Smith SJ. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males. American Journal of Men’s Health. 2019;13(2).
Abhijit Deshpande, Nushafreen Irani, Ratna Balkrishnan, Irin Rosanna Benny. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults. Sleep Medicine, Volume 72, 2020, Pages 28-36, ISSN 1389-9457
Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract—A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. Journal of Clinical Medicine. 2021; 10(16):3644.
Antony, Benny; Benny, Merina; Kuruvilla, Binu T.; Sebastian, Anu; Aravindakshan Pillai, Anu A.; Joseph, Biji; Edappattu Chandran, Sheeja. Development and validation of an RP-HPLC method for the simultaneous determination of total withanolide glycosides and Withaferin A in Withania somnifera (Ashwagandha). Current Chromatography, Volume 7, Number 2, 2020, pp. 106-120(15).
Antony, B., M. Benny, B. T. Kuruvilla, N. K. Gupta, A. Sebastian, and S. Jacob. “ACUTE AND SUB CHRONIC TOXICITY STUDIES OF PURIFIED WITHANIA SOMNIFERA EXTRACT IN RATS”. International Journal of Pharmacy and Pharmaceutical Sciences, vol. 10, no. 12, Dec. 2018, pp. 41-46
Sindgi Vasudeva Murthy, Syeda Nishat Fathima, and Rakesh Mote. Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in In Vitro – In Vivo Experimental Models. Prev Nutr Food Sci 2022; 27(1): 108-120. Published March 31, 2022.