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APEX GLUTATHIONE: THE RESEARCH

APEX glutathione: the research 

Scroll down to view the references for the studies on the proprietary ingredients in APEX Glutathione and learn more about what makes it such an extraordinary product.

Bacognize® Standardized Bacopa Extract

bacopa supports glutathione production in the brain and promotes healthy neurotransmitter generation

Bacognize® is a clinically-researched standardized extract of the Ayurvedic herb Bacopa monnieri.

Although many may be familiar with bacopa’s positive effects on mood and focus, few are aware that it also works with the body’s glutathione system.

Bacognize® has been clinically proven to enhance memory and focus.  It is sustainably grown in India and standardized via HPLC to contain serotonin-active bacopa glycosides and other bioactive phytochemicals.

The subject of 6 studies, Bacognize® supports:

  • Multi-antioxidant activation through promotion of NRF2
  • Enhanced activity of the Glutathione S-Transferase (GST) enzyme, helping glutathione bind to toxins
  • Enhanced activity of the Glutathione Peroxidase (GPx) enzyme, assisting glutathione with the neutralization of free radicals
  • Optimal memory and cognitive performance by promoting healthy levels of acetylcholine
  • Healthy mood by promoting serotonin signaling (via SABGs: Serotonin-Active Bacopa Glycosides)
  • Optimal stress response and calm focus by promoting healthy GABA levels
  • Healthy neurological inflammation response

REFERENCES

Hall B et al. Pharmacology of Bacopa monnieri (Bacognize®) at 5HT1a and 5HT2a receptors.Poster presentation. Am Soc Pharmaco Absts. 2005. 85-83. doi: 10.1007/98-3-7643-8561-3

MD Navneet Kumar. Efficacy of standardized extract of Bacopa monnieri (Bacognize®) on cognitive functions of
medical students: A six week, randomized placebo-controlled trial. Dept of Clinical Pharmacol Thera, Nizam’s Institute of Medical Sciences.

Thawani & Goswami, Shishir & Saoji, Anand & Kumar, Navneet & Thawani, Vijay & Tiwari, Meenal & Thawani, Manasi. (2011). International Journal of Collaborative Research on Internal Medicine and Public Health. 3.

Headapohl et al. Effects of Bacopa monnieri (Bacognize®) on memory and cognitive function in healthy older adults: A double-blind placebo-controlled study. Unpublished Manuscript

Goswami S, Saoji A, Kumar N, Thawani V, Tiwari M, Thawani M. (2011) International Journal of Collaborative Research on Internal Medicin & Public Helath.  3(4): 285-293

Hingorani L, Patel S, Ebersole B (2012) Sustained cognitive effects and safety of HPLC-standardized Bacopa Monnieri extract: A randomized, placebo controlled clinical trial Planta Med 78 – PH22 DOI: 10.1055/s-0032-1320681

3x absorption Ginkgo phytosome

ginkgo: a classic herb, upgraded for enhanced bioavailability

Ginkgo Biloba leaf has been revered for millennia for its ability to support healthy blood flow, cognitive function, and mood.

Many people know of its ability to support brain health, but few know that part of its essential mechanism of action is that it’s able to upregulate glutathione by supporting the activity of enzymes called Glutathione-S-transferases (GSTs).

Ginkgo also supports healthy mood and focus by promoting the activity of critical neurotransmitters such as serotonin and dopamine.

The special Ginkgo Phytosome used in APEX Glutathione absorbs three times better than a standard ginkgo extract because it’s been blended with phospholipids from sunflower seeds.

The subject of 3 studies, Ginkgo Phytosome supports:

  • Healthy glutathione activity in the brain by promoting the activity of Glutathione-S-transferases (GSTs)
  • Mood health by supporting dopamine and serotonin
  • Healthy inflammation response
  • Cardiovascular health by promoting healthy blood flow throughout the body
  • Memory and focus by supporting circulation within the brain and promoting the activity of acetylcholine

REFERENCES

Muir, A. H., Robb, R., McLaren, M., Daly, F., & Belch, J. J. (2002).  Vascular medicine (London, England), 7(4), 265–267.

d’Alessandro, Aldo. (2015). Acta Phlebologica. 16. 83-92.

Mauri, P., Simonetti, P., Gardana, C., Minoggio, M., Morazzoni, P., Bombardelli, E., & Pietta, P. (2001). Liquid chromatography/atmospheric pressure chemical ionization mass spectrometry of terpene lactones in plasma of volunteers dosed with Ginkgo biloba L. extracts. Rapid communications in mass spectrometry : RCM, 15(12), 929–934.